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This report outlines that although decriminalization of drug use and possession for personal use increases the provision, access and uptake of health and harm reduction services, criminalization and severe punishments remain commonplace. An estimated one in five people in prison globally are incarcerated for drug-related offences, around 80% of whom are in prison for possession for personal use alone. In addition, the report lists 35 countries that retain the death penalty for drug-related offences.